Which of the following is a known risk factor for colon cancer?

Smoking is recognized as a significant risk factor for colon cancer. Research has consistently shown that tobacco use contributes to the development of various cancers, including colorectal cancer. The carcinogenic compounds found in tobacco smoke have been linked to DNA damage and an increased likelihood of tumor formation in the colon.

In contrast, regular physical activity, a high-fiber diet, and low alcohol intake are typically associated with a reduced risk of colon cancer. Engaging in regular exercise can help maintain a healthy weight and improve gut health, while a high-fiber diet promotes regular bowel movements and may facilitate the removal of potential carcinogens from the digestive tract. Additionally, low alcohol intake is associated with lower cancer risk, particularly for several types of cancer, including colorectal cancer. Thus, smoking stands out as the only choice listed that increases the likelihood of developing colon cancer.