Which medication is used to treat extravasation from anthracyclines such as Doxorubicin?

Totect, also known as Dexrazoxane, is specifically indicated for the treatment of extravasation injuries caused by anthracycline chemotherapy, such as Doxorubicin. Extravasation refers to the leakage of a chemotherapy agent into the surrounding tissue, which can lead to severe local tissue damage and necrosis. Totect works by chelating free radicals formed in the tissue as a result of these agents, reducing oxidative stress and potential tissue damage associated with their extravasation.

The use of Totect is important in managing this type of extravasation because it can help limit injury and encourage healing. Administering this medication as soon as possible after the occurrence of extravasation can significantly improve outcomes for affected patients. In contrast, other options listed may not have the same level of efficacy or are not indicated for this type of complication.