Which lifestyle factor significantly increases the risk of mucositis for patients undergoing chemotherapy?

History of alcohol and tobacco use is a significant lifestyle factor that increases the risk of mucositis in patients undergoing chemotherapy. Patients who smoke tobacco or consume alcohol are more likely to have compromised oral health and mucosal integrity. Both substances can lead to inflammation and irritation of the mucosal lining, making patients more susceptible to developing mucositis during chemotherapy, which can further exacerbate discomfort and complicate treatment.

In contrast, high levels of hydration, regular dental check-ups, and consumption of balanced meals are all factors that can help mitigate the risk of mucositis. Staying well-hydrated supports oral tissue health, regular dental check-ups can help prevent and manage oral issues, and a balanced diet provides essential nutrients that are crucial for maintaining mucosal integrity and overall health. Thus, while managing these lifestyle factors is important, a history of alcohol and tobacco use poses a notably higher risk.