What is a common characteristic of hypersensitivity reactions to platinum drugs?

Study for the ONS/ONCC Chemotherapy Immunotherapy CAQ Renewal Test. Test with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Hypersensitivity reactions to platinum drugs, such as cisplatin and carboplatin, are characterized by their occurrence after multiple treatments rather than immediately following the first dose. Initial administration of these agents may not elicit an allergic response, but subsequent exposures can sensitize the patient and provoke a hypersensitivity reaction. This is particularly common in patients who have received cumulative doses of platinum agents, as the body can develop an immune response over time.

The gradual build-up of sensitization can lead to reactions that vary in severity, timing, and presentation based on the individual’s immune system and previous exposure history. Hence, the occurrence of hypersensitivity reactions is strongly associated with multiple treatments rather than a singular event at first exposure. This underscores the importance of close monitoring and patient history when administering these chemotherapy agents repeatedly.

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